Thermo Fisher Scientific Frizzled 10 Polyclonal Antibody
Frizzled 10 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot과 Immunocytochemistry에 적합합니다. 인간, 생쥐, 비인간 영장류 반응성을 가지며, 고순도 Affinity Chromatography로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FZD10 (Accession Q9ULW2), corresponding to amino acid residues P151–V201 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850439 |
Product Specific Information
Antibody detects endogenous levels of total FZD10.
Target Information
FZD10 (Frizzled-10) is a 581 amino acid protein belonging to the G-protein coupled receptor Fz/Smo family.
It contains:
- Signal peptide
- Cysteine-rich domain in the N-terminal
- Seven transmembrane domains
- C-terminal PDZ domain-binding motif
Biological Role:
FZD10 is involved in transduction and intercellular transmission of polarity information during tissue morphogenesis in differentiated tissues, acting as a receptor for Wnt proteins.
Expression Profile:
Highly expressed in placenta, fetal kidney, fetal lung, brain cerebellum, cerebral cortex, medulla, and spinal cord.
Low expression in total brain, frontal lobe, temporal lobe, putamen, adult brain, heart, lung, and skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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