
Thermo Fisher Scientific IL10RA Monoclonal Antibody (OTI1C12), TrueMAB
Human IL10RA 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot에 적합. TrueMAB 포맷으로 높은 특이성과 안정성 제공. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol 버퍼에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C12 |
| Immunogen | Full length human recombinant IL10RA protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The IL10RA gene encodes a receptor for interleukin 10, structurally related to interferon receptors. It mediates the immunosuppressive signal of IL10, inhibiting synthesis of proinflammatory cytokines. This receptor promotes survival of progenitor myeloid cells through the IRS-2/PI3K/AKT pathway and activates tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants have been identified, one protein-coding and one non-coding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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