Thermo Fisher Scientific TSC22D3 Monoclonal Antibody (OTI1E11), TrueMAB
TSC22D3 단백질을 인식하는 Mouse Monoclonal Antibody로, WB 및 ICC/IF에 적합. Glucocorticoid 및 IL-10에 의해 유도되는 항염증 신호 연구에 활용 가능. 1 mg/mL 농도의 액상 항체로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E11 |
| Immunogen | Full length human recombinant protein of human TSC22D3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules.
TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such as NF-Kappa-B and AP-1. It functions as a transcriptional co-activator for various nuclear receptors and NF-Kappa-B, and is also involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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