
Thermo Fisher Scientific ARHGAP42 Polyclonal Antibody
ARHGAP42 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot에 적합하며, 인간 시료에서 반응합니다. 고순도의 친화 크로마토그래피 정제 제품으로, -20°C 보관 및 습빙 배송됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ARHGAP42 (Accession A6NI28), corresponding to amino acid residues K767–S817 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853906 |
Product Specific Information
Antibody detects endogenous levels of total ARHGAP42.
Target Information
This gene encodes a Rho GTPase-activating protein (RhoGAP) and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells, and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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