Thermo Fisher Scientific TEM7 Polyclonal Antibody
Human TEM7 단백질에 특이적인 rabbit polyclonal antibody로, IHC(P) 등 다양한 연구 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 종양 혈관 내피 관련 연구에 활용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human TEM7. Recombinant protein control fragment (Product #RP-90375) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856189 |
Product Specific Information
Immunogen sequence:
RSCDACMSSD LTFNCSWCHV LQRCSSGFDR YRQEWMDYGC AQEAEGRMCE DFQDEDHDSA SPDTSFSPYD GDLTTTSSSL FIDSLTTEDD TKLNPYAGGD GLQNNLSPKT KGTPVHLG
Target Information
Using SAGE (Serial Analysis of Gene Expression) technology, St. Croix et al. identified 46 genes whose expression is specifically elevated in tumor-associated endothelium. Nine of these genes were prominently expressed only in tumor endothelial cells (EC), and named Tumor Endothelial Markers (TEMs, TEM 1–9).
TEM7 transcripts are specifically expressed in the endothelium of colorectal, lung, pancreas, breast, and brain cancers, both primary and metastatic. Other family members (TEM1, 3, 4, 5, 8, and 9) show similar expression patterns in lung and brain tumors and liver metastasis.
These genes may serve as valuable resources for studies of human angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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