Thermo Fisher Scientific CD200 Monoclonal Antibody (325516)
인간 CD200 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체. Flow Cytometry에 적합하며 비교종 반응 없음. 동결건조 형태로 제공되며 PBS+trehalose buffer 사용. 연구용으로만 사용 가능.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 0.25 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 325516 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human CD200 (Gln31–Gly232) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608821 |
Additional Formats
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant mouse CD200 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains and belongs to the immunoglobulin superfamily.
It is a broadly distributed cell surface glycoprotein that interacts with CD200R on myeloid cells to inhibit macrophage activation.
Homologues of CD200 have been identified in herpesviruses and poxviruses. Studies in mouse and rat suggest CD200 regulates myeloid cell activity and provides inhibitory signaling for macrophages in diverse tissues.
Multiple alternatively spliced transcript variants encoding different isoforms of CD200 have been found.
Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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