Thermo Fisher Scientific DTX3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DTX3. Recombinant protein control fragment (Product #RP-101968). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DTX3,uniProtId:Q8N9I9-1,ncbiNodeId:9606,antigenRange:149-202,antigenLength:347,antigenImageFileName:PA5-63762_DTX3_Q8N9I9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63762_DTX3_Q8N9I9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640815

Product Specific Information

Immunogen sequence: LPPRLREEAE EQESTCPICL GEIQNAKTLE KCRHSFCEGC ITRALQVKKA CPMC

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

Target Information

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.