Thermo Fisher Scientific DTX3 Polyclonal Antibody
Human DTX3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)와 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 버퍼에 보존. Notch 신호 조절 연구에 적합한 연구용 항체.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DTX3. Recombinant protein control fragment (Product # RP-101968) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640815 |
Product Specific Information
Immunogen sequence:
LPPRLREEAE EQESTCPICL GEIQNAKTLE KCRHSFCEGC ITRALQVKKA CPMC
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 96%
Target Information
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations.
Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context.
Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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