Thermo Fisher Scientific PHF21A Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PHF21A. Recombinant protein control fragment (Product #RP-93601). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PHF21A,uniProtId:Q96BD5-1,ncbiNodeId:9606,antigenRange:578-676,antigenLength:680,antigenImageFileName:PA5-54829_PHF21A_Q96BD5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54829_PHF21A_Q96BD5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645491

Product Specific Information

Immunogen sequence: QEREQLEQKV KQLSNSISKC MEMKNTILAR QKEMHSSLEK VKQLIRLIHG IDLSKPVDSE ATVGAISNGP DCTPPANAAT STPAPSPSSQ SCTANCNQG

Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 93%.

Target Information

PHF21A (PHD finger protein 21A) is a component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, PHF21A may act as a scaffold.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.