
Thermo Fisher Scientific MRPL48 Monoclonal Antibody (OTI8E1)
MRPL48 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(파라핀 절편)에 사용 가능. 인간 시료에 반응하며, 고순도의 액상 형태로 제공. 연구용으로 미토콘드리아 리보솜 단백질 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E1 |
| Immunogen | Full length human recombinant protein of MRPL48 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724736 |
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and function in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition—opposite to that of prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes do not contain a 5S rRNA. The proteins composing mitoribosomes vary significantly among species, both in sequence and biochemical properties, complicating recognition by sequence homology. The MRPL48 gene encodes a 39S subunit protein, and a pseudogene corresponding to this gene is located on chromosome 6p.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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