Thermo Fisher Scientific Human TSPY1 Synthetic Peptide
인간 TSPY1 단백질의 카르복시 말단 20개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. 항체 차단 실험에 사용되며, Human 시료에 반응합니다. PBS 완충액 내 0.1% BSA와 0.02% sodium azide를 포함하고, -20°C에서 보관합니다.
- 카탈로그번호
- PEP1525
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 20 amino acids near the carboxy terminus of human TSPY1L.
PEP-1525 can be used as a blocking peptide with polyclonal antibody PA5-34483.
Target Information
Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma.
Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor.
This suggests that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development.
Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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