Thermo Fisher Scientific NDUFB6 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,500

Immunoprecipitation (IP)

• Tested Dilution: 2–10 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, predicted to react with Bovine, Orangutan, Gorilla, and Chimpanzee

Target Information

Methylation of cytosine at CpG dinucleotides is a common feature of many higher eukaryotic genomes. Increasing evidence indicates that recruitment of histone deacetylase complexes by methyl-CpG-binding proteins (MeCP) is a major mechanism of methylated DNA silencing. P66, a zinc finger-containing protein, is one of the components of the MeCP1 complex. P66 and p68, the two components of MeCP1, are different forms of the same zinc finger-containing protein and are conserved from C. elegans to humans. Homologs of p66 from different organisms reveal two highly conserved regions, CR1 and CR2. While CR1 is involved in the association of p66 with other MeCP1 components, CR2 plays an important role in targeting p66 and MBD3 to specific loci.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.