Thermo Fisher Scientific Aquaporin 4 Polyclonal Antibody
Thermo Fisher Scientific의 Aquaporin 4 Polyclonal Antibody는 Rat 조직에서 검증된 Rabbit IgG 폴리클로날 항체입니다. WB, IHC, ICC/IF에 사용 가능하며, -20°C 보관 및 50 µL 탈이온수로 재구성합니다. 세포 내 수분 이동 연구용으로 적합합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | - |
| Immunohistochemistry (IHC) | 1:200 | View 2 publications |
| Immunocytochemistry (ICC/IF) | 1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)HVIDIDRGDEKKGKD, corresponding to amino acid residues 300–314 of rat AQP4 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735469 |
Product Specific Information
- Product is shipped at room temperature as a lyophilized powder.
- Store at -20°C upon receipt.
- Reconstitute using 50 µL deionized water.
Target Information
In skeletal muscle, AQP4 (aquaporin 4, also known as mercurial insensitive water channel) localizes to the sarcolemma of fast-twitch muscle fibers.
Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane.
This function is conserved in animals, plants, and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10.
Aquaporins are widely distributed, and it is not uncommon for more than one type of AQP to be present in the same cell.
Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9, and one of the two AQP10 transcripts are also permeable to urea and glycerol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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