Thermo Fisher Scientific KLHL1 Polyclonal Antibody
Thermo Fisher Scientific KLHL1 Polyclonal Antibody는 Rat KLHL1 단백질을 인식하는 Rabbit IgG 기반 항체입니다. Western blot에 적합하며, 액상 형태로 0.5 mg/mL 농도 제공. KLHL1 단백질의 신경 관련 연구 및 단백질 발현 분석에 활용 가능.
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- PA568640
- 판매단위
- pk
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Thermo Fisher Scientific KLHL1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of rat KLHL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689925 |
Product Specific Information
This target displays homology in the following species:
Cow: 79% | Horse: 93% | Human: 100% | Mouse: 100% | Pig: 93% | Rabbit: 100% | Rat: 100%
Target Information
The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of proteins that bind actin, form dimers, and often act as actin-organizing proteins.
Based on the presence of anti-sense RNA spanning the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 may be involved in this disease and that regulation of KLHL1 protein could be affected by antisense RNA expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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