
Thermo Fisher Scientific GFER Polyclonal Antibody
Thermo Fisher Scientific의 GFER Polyclonal Antibody는 인간 및 마우스 시료에 반응하며, Western blot과 유세포분석(Flow Cytometry)에 적합합니다. KLH 결합 합성 펩타이드를 면역원으로 사용한 토끼 다클론 항체로, 2 mg/mL 농도의 액상 형태로 제공됩니다. 연구용 전용 제품입니다.
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- PA548256
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Flow Cytometry (Flow) | 1:10–1:50 | — |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 173–202 amino acids from the C-terminal region of human GFER |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633714 |
Target Information
Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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