Thermo Fisher Scientific CNPY3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A portion of amino acids 200-250 of human PRAT4A if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CNPY3,uniProtId:Q9BT09-1,ncbiNodeId:9606,antigenRange:200-250,antigenLength:278,antigenImageFileName:PA5-23282_CNPY3_Q9BT09-1_Rabbit.svg,antigenImageFileNamePDP:PA5-23282_CNPY3_Q9BT09-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

whole serum with 50% glycerol

Contains

0.025% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2540806

Target Information

PRAT4A is a novel protein belonging to the canopy family with a saposin B-type domain. It is an accessory molecule required for microbial recognition by Toll-like receptor (TLR), and mediates TLR dependent immune responses. Though the exact function of PRAT4A is still unknown, reports suggest that it is associated with the immature form of TLR4 and regulates the cell surface expression of this TLR. PRAT4A, a secreted protein, also has a role in TLR4 maturation and glycosylation. PRATA4 is usually present in endoplasmic reticulum and plays an active role in regulating the subcellular distribution and response of multiple TLRs and is required for both innate and adaptive immune responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.