Thermo Fisher Scientific Synoviolin Polyclonal Antibody
Western blot 및 Immunoprecipitation에 적합한 HRD1/Synoviolin 폴리클로날 항체. 사람과 생쥐 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C에서 보관. 세포 사멸 억제 단백질 연구용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 567 and 617 of Human Synovial Apoptosis Inhibitor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly in brain, pancreas, liver, kidney, and skeletal muscle. Synoviolin/Hrd1, expressed in rheumatoid synovium, is reported as a causative factor for arthropathy by triggering synovial cell outgrowth through anti-apoptotic effects. HRD1 contains one ring-type zinc finger.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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