Thermo Fisher Scientific CD4 Monoclonal Antibody (RM4-5), Pacific Blue

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

Assay-dependent

View 8 publications 8 publications

Miscellaneous PubMed (Misc)

-

View 3 publications 3 publications

Product Specifications

Species Reactivity

Mouse

Published species

Mouse

Host/Isotype

Rat / IgG2a

Class

Monoclonal

Type

Antibody

Clone

RM4-5

Immunogen

Mouse CD4

Conjugate

Pacific Blue™ Pacific Blue™ Pacific Blue™

View additional formats

• Alexa Fluor 405
• APC
• APC-Cyanine5.5
• Pacific Orange
• PE-Texas Red
• Qdot 605
• Qdot 800
• TRI-COLOR
• Request custom conjugation

Excitation/Emission Max

404/455 nm View spectra

Form

Liquid

Concentration

0.1 mg/mL

Purification

purified

Storage buffer

PBS with 4mg/mL BSA

Contains

0.1% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10372505

Target Information

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.