Thermo Fisher Scientific TCEB1 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human TCEB1 (Elongin C) for WB, IHC, and IP applications. Recognizes residues 1–50 of TCEB1, predicted to cross-react with Rat and Bovine. Supplied as liquid, 1 mg/mL, stored at 4°C. For research use only.
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Thermo Fisher Scientific TCEB1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1–50 of Human Transcription elongation factor B polypeptide 1 (TCEB1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine
Target Information
TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex.
The SIII complex is composed of elongins A/A2, B, and C, which activate elongation by RNA polymerase II by suppressing transient pausing.
Elongin A serves as the transcriptionally active component, while elongins B and C act as regulatory subunits.
Elongin A2 is specifically expressed in the testis and forms a stable complex with elongins B and C.
The von Hippel–Lindau tumor suppressor protein binds to elongins B and C, thereby inhibiting transcription elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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