Thermo Fisher Scientific CACNG3 Polyclonal Antibody
Rabbit polyclonal antibody targeting CACNG3, validated for Western blot. Recognizes calcium channel gamma-3 involved in neuronal calcium signaling. Supplied as liquid, unconjugated, purified by ammonium sulfate precipitation. For research use only.
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Thermo Fisher Scientific CACNG3 Polyclonal Antibody
Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH, corresponding to the rat calcium channel gamma3 subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2069735 |
Product Specific Information
A suggested positive control for this product is rat brain lysate.
Target Information
Calcium Channel gamma-3 is a member of voltage-dependent calcium channels (VDCCs) that enable neurons to regulate calcium signaling in specific cellular regions. N-Type VDCCs exist before birth, implying roles in migration, while postnatal expression supports synaptic transmission in hippocampal fields.
Gamma-3 acts as a type I transmembrane AMPA receptor regulatory protein (TARP), regulating trafficking and channel gating of AMPA receptors. It belongs to an eight-member subfamily of the PMP-22/EMP/MP20 family.
Dysfunction of the Calcium Channel gamma-3 gene is associated with susceptibility to childhood absence epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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