Thermo Fisher Scientific FOXN1 Polyclonal Antibody
FOXN1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western Blot에 최적화되어 있으며 인간, 마우스, 랫트 반응성을 가집니다. 고순도 항원 친화 크로마토그래피로 정제되었고, 0.8 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 585–648 of FOXN1 (Uniprot ID: O15353) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7) with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C; avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152532 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2, A549, H1299, HCT116
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FOXN1 is a 648 amino acid protein belonging to the winged helix/forkhead family. It contains one fork-head DNA-binding domain and acts as a transcriptional regulator involved in development.
FOXN1 directs lineage choices of multi-potential progenitor epithelial cells and regulates genes involved in lympho-epithelial interactions. It modulates keratinocyte differentiation in hair follicles and nail apparatus. Defects in FOXN1 lead to T-cell immunodeficiency, congenital alopecia, nail dystrophy, and thymic dysgenesis.
⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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