Thermo Fisher Scientific PPP2R1B Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Target Information

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis, and apoptosis. Protein phosphatases play a key role in this process. The protein phosphatase (PP) holoenzyme is typically a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit.

Four major families of protein phosphatase catalytic subunits have been identified: PP1, PP2A, PP2B (calcineurin), and PP2C. An additional subunit, PPX (also known as PP4), is considered part of a novel PP family. The PP2A family includes PP2A alpha and PP2A beta subfamily members. The PP2A catalytic subunit associates with various regulatory subunits such as PP2A-A alpha and -A beta, PP2A-B alpha and -B beta, PP2A-C alpha and -C beta, and PP2A-B56 alpha and -B56 beta.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.