Thermo Fisher Scientific PAX7 (Rhabdomyosarcoma Marker) Recombinant Mouse Monoclonal Antibody (rPAX7/9325)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

rPAX7/9325

Immunogen

Recombinant fragment (aa301-505) of human PAX7 protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PAX7,uniProtId:P23759-3,ncbiNodeId:9606,antigenRange:301-505,antigenLength:505,antigenImageFileName:5081-MSM6-P0_PAX7_P23759-3_House_mouse.svg,antigenImageFileNamePDP:5081-MSM6-P0_PAX7_P23759-3_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control:Human rhabdomyosarcoma (RMS) or testicular carcinoma.

Cellular Location: Nucleus.

Target Information

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.