
Thermo Fisher Scientific PARN Monoclonal Antibody (OTI1G5)
PARN 단백질을 표적으로 하는 Thermo Fisher Scientific의 마우스 단일클론 항체. Western blot 및 IHC(P) 검증 완료. 고순도 친화 크로마토그래피 정제, 1 mg/mL 액상 형태. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of PARN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724938 |
Target Information
The protein encoded by this gene is a 3'-exoribonuclease, similar to the RNase D family of 3'-exonucleases. It preferentially degrades poly(A) tails of mRNAs, initiating mRNA decay in eukaryotic cells. This protein also participates in silencing certain maternal mRNAs during oocyte maturation and early embryonic development, and in nonsense-mediated decay (NMD) of mRNAs with premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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