Thermo Fisher Scientific Human ITGA4 Synthetic Peptide
휴먼 ITGA4 합성 펩타이드로 인간 인테그린 알파4 단백질 연구에 사용됨. 폴리클로날 항체 PA5-20600의 블로킹 펩타이드로 활용 가능. PBS 버퍼에 BSA와 sodium azide 포함, 액상 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP0720
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human ITGA4 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the center of human integrin alpha 4.
PEP-0720 can be used as a blocking peptide with polyclonal antibody PA5-20600.
Target Information
The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of alpha and beta chains. The alpha4 chain associates with either beta1 or beta7 chain.
It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 are located on the alpha4 chain. These ligands include Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha4beta7.
Recent studies have shown that the HIV-1 envelope can mimic Madcam by binding to and signaling through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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