Thermo Fisher Scientific RBM5 Polyclonal Antibody
Thermo Fisher Scientific의 RBM5 Polyclonal Antibody는 인간 RBM5 단백질을 인식하는 토끼 IgG 항체로, WB, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RBM5. Recombinant protein control fragment (Product #RP-89626). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646397 |
Product Specific Information
Immunogen sequence:
DKRVSRTERS GRYGSIIDRD DRDERESRSR RRDSDYKRSS DDRRGDRYDD YRDYDSPERE RERRNSDRSE DGYHSDGDYG EHDYRHDISD ERESKTIMLR GLPITITESD IREMMESFEG PQPADVRLMK RKTGVSRGFA FVEFYHL
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the hematopoietic system of mice, DEF-3 expression is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both proteins contain two zinc finger motifs, a bipartite nuclear signal, and two RNA binding motifs, and are capable of specifically binding poly(G) RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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