
Thermo Fisher Scientific Neuropeptide Q2/NPQ2 Polyclonal Antibody
Thermo Fisher Scientific의 Neuropeptide Q2/NPQ2 Polyclonal Antibody는 기니피그 유래 IgG 항체로, IHC에 적합합니다. Spexin 관련 연구용으로 사용되며, 심혈관·신장 기능 및 에너지 대사 조절 연구에 활용됩니다. 액상 형태로 제공되며, 4°C~−20°C 보관이 권장됩니다.
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Thermo Fisher Scientific Neuropeptide Q2/NPQ2 Polyclonal Antibody
Applications
- Immunohistochemistry (IHC)
Tested Dilution: 1:100–1:600
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Guinea pig / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | [NH2-APQRLSE]-[K]7-bAla-OH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Target Information
Spexin hormone acts as a central modulator of cardiovascular and renal function and nociception. It also plays a role in energy metabolism and storage and inhibits adrenocortical cell proliferation with minor stimulation on corticosteroid release.
Spexin is cleaved into two chains — Spexin-1 and Spexin-2.
- Spexin-1: Ligand for galanin receptors GALR2 and GALR3. Induces increased arterial blood pressure, decreased heart rate and renal excretion, and delayed natriuresis. Also induces contraction of muscarinic-like stomach smooth muscles, reduces food consumption and body weight, and inhibits long-chain fatty acid uptake into adipocytes.
- Spexin-2: Decreases heart rate without changing arterial pressure and increases urine flow rate.
Both Spexin-1 and Spexin-2 induce antinociceptive activity when administered intraventricularly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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