Thermo Fisher Scientific FAM96A Polyclonal Antibody
Thermo Fisher Scientific의 FAM96A Polyclonal Antibody는 인간 FAM96A 단백질에 특이적인 토끼 다클론 항체입니다. WB, IHC(P), ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 내 철-황 단백질 조립 복합체 연구에 활용됩니다.
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Thermo Fisher Scientific FAM96A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAM96A. Recombinant protein control fragment (Product #RP-98168) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641483 |
Product Specific Information
Immunogen sequence:
RIMEEKALEV YDLIRTIRDP EKPNTLEELE VVSESCVEVQ EINEEEYLVI IRFTPTVPHC SL
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 92%
Target Information
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, which mediates incorporation of iron-sulfur clusters into extramitochondrial Fe/S proteins (PubMed:23891004). As part of the CIA complex, collaborates with CIAO1 to mature ACO1 and stabilize IREB2, linking cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May be involved in chromosome segregation via sister chromatid cohesion and may induce apoptosis in collaboration with APAF1 (PubMed:25716227). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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