Thermo Fisher Scientific GNB3/GNB4 Polyclonal Antibody, Biotin

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1-0.3 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence SGHDNRVSCLGVT (aa 309-321). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GNB3/GNB4,uniProtId:P16520-1,ncbiNodeId:9606,antigenRange:309-321,antigenLength:340,antigenImageFileName:PA5-142624_GNB3GNB4_P16520-1_Goat.svg,antigenImageFileNamePDP:PA5-142624_GNB3GNB4_P16520-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2933270

Product Specific Information

Additional Information: This antibody is expected to recognize GNB3 & GNB4 (GeneID: 2784, 59345; ProteinID: NP_002066.1; NP_067642.1).

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

Target Information

Heterotrimeric guanine nucleotide-binding proteins in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.