Thermo Fisher Scientific TGR5 Polyclonal Antibody
Rabbit polyclonal antibody targeting TGR5 (GPBAR1) for Western blot applications. Recognizes rat GPBAR1 amino acids 282–296. Supplied lyophilized, reconstituted with 50 µL deionized water. Stored at -20°C; shipped on wet ice. For research use only.
- 카탈로그번호
- PA577294
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Tested dilution 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)GDQRYTAPWRTAAQR, corresponding to amino acid residues 282–296 of rat GPBAR1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735791 |
Product Specific Information
- Product is shipped at room temperature as a lyophilized powder.
- Store at -20°C upon receipt.
- Reconstitution: add 50 µL of deionized water.
Target Information
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. It functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces intracellular cAMP production, activates MAP kinase signaling, and triggers receptor internalization. The receptor is involved in suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing produces multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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