Thermo Fisher Scientific PRAME nuclear receptor transcriptional regulator Recombinant Rabbit Monoclonal Antibody (PRAME/8558R)
PRAME 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, 인체 멜라노마 및 백혈병 연구에 적합. HEK293 세포에서 발현되며 IHC(P) 및 IHC(PFA) 실험에 사용 가능. 고순도 Protein A/G 정제, 안정적 PBS 버퍼 보존.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PRAME/8558R |
| Immunogen | Recombinant fragment (around aa100–509) of human PRAME protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an antigen predominantly expressed in human melanomas and recognized by cytolytic T lymphocytes. It is not expressed in normal tissues except testis. The expression pattern is similar to other CT antigens such as MAGE, BAGE, and GAGE, but unlike those, it is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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