Thermo Fisher Scientific POLK Polyclonal Antibody
Human POLK 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보관됩니다. 연구용으로만 사용되며, DNA 손상 복구 관련 연구에 활용 가능합니다.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human POLK (Product #RP-106766) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791486 |
Product Specific Information
Immunogen sequence:
FAIAKELLKT EIDADFPHPL RLRLMGVRIS SFPNEEDRKH QQRSIIGFLQ AGNQALSATE CTLEKTDKDK FVKPLEMSHK KSFFDKKRSE RKWSHQDTFK CEAVNKQSFQ TSQPFQVL
Target Information
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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