Thermo Fisher Scientific CYFIP1 Polyclonal Antibody
CYFIP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1203 and 1253 of human Cytoplasmic FMR1 Interacting Protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Component of the CYFIP1–EIF4E–FMR1 complex which binds to the mRNA cap and mediates translational repression. In this complex, CYFIP1 acts as an adapter between EIF4E and FMR1, promoting translation repression activity of FMR1 in the brain by mediating its association with EIF4E and mRNA. It is involved in the formation of membrane ruffles, lamellipodia protrusions, and axon outgrowth. CYFIP1 binds to F-actin but not RNA, functioning as a regulator of epithelial morphogenesis and may act as an invasion suppressor in cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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