Thermo Fisher Scientific TCTEX1D4 Polyclonal Antibody
Rabbit polyclonal antibody targeting TCTEX1D4 for ICC/IF applications. Recognizes human protein with cross-reactivity to mouse and rat. Supplied as liquid, unconjugated, 0.1 mg/mL in PBS with glycerol. For research use only.
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Applications and Tested Dilution
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 148–221). Recombinant protein control fragment: RP-109814 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092188 |
Product Specific Information
- Immunogen sequence:
LVRELCEQVH VRLRELSPPR YKLVCSVVLG PRAGQGVHVV SRALWDVARD GLASVSYTNT SLFAVATVHG LYCE - Antigen sequence identity:
Mouse 74%; Rat 76%
Target Information
Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12-subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains, and several light chains. It performs essential cellular functions such as organelle transport and centrosome assembly.
TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na⁺ CP type X (SCN10A). TCTEX1D4, also known as TCTEX2 beta, interacts with members of the TGF-beta receptor family and, when overexpressed, inhibits TGF-beta signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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