Thermo Fisher Scientific TCTEX1D4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 148-221. Recombinant protein control fragment (Product #RP-109814). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TCTEX1D4,uniProtId:Q5JR98-1,ncbiNodeId:9606,antigenRange:148-221,antigenLength:221,antigenImageFileName:PA5-144835_TCTEX1D4_Q5JR98-1_Rabbit.svg,antigenImageFileNamePDP:PA5-144835_TCTEX1D4_Q5JR98-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3092188

Product Specific Information

Immunogen sequence: LVRELCEQVH VRLRELSPPR YKLVCSVVLG PRAGQGVHVV SRALWDVARD GLASVSYTNT SLFAVATVHG LYCE

Antigen sequence identity: Mouse 74%; Rat 76%

Target Information

Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D4, also called TCTEX2 beta, interacts with different members of the TGF-beta receptor family, and when overexpressed, inhibits TGF-beta signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.