Thermo Fisher Scientific PSMB10 Polyclonal Antibody
Thermo Fisher Scientific의 PSMB10 Polyclonal Antibody는 인간 단백질에 반응하는 Rabbit IgG 기반 항체로 Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PSMB10. Recombinant protein control fragment (Product #RP-95875). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646056 |
Product Specific Information
Immunogen sequence:
AGILGDLGSG GNVDACVITK TGAKLLRTLS SPTEPVKRSG RYHFVPGTTA VLTQTVKPLT LELVEETVQA MEVE
Antigen sequence identity:
- Mouse: 80%
- Rat: 77%
Target Information
The 20S proteasome is a protease complex responsible for cytosolic protein degradation and generation of peptide ligands for MHC class I molecules. Upon IFN-gamma stimulation, three constitutive subunits (LMP2, LMP7, MECL-1) replace standard proteasome subunits to form immunoproteasomes, enhancing antigen processing efficiency. Various combinations of these subunits can create up to 36 unique proteasome subsets, potentially influencing cleavage specificity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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