
Thermo Fisher Scientific PARP (Cleaved Asp214, Asp215) Polyclonal Antibody, FITC
FITC로 표지된 Cleaved PARP (Asp214, Asp215) 폴리클로날 항체로, Western blot, IHC, ICC/IF, Flow Cytometry에 사용 가능. 인간 및 마우스 시료에서 검증됨. -20°C에서 보관하며 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | View 3 publications |
| Immunohistochemistry (IHC) | Assay-dependent | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Flow Cytometry (Flow) | Assay-dependent | View 7 publications |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Chemically synthesized peptide corresponding to N-terminus of cleavage site (214/215) of human PARP |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Storage conditions | -20°C, store in dark |
| Shipping conditions | Wet ice (domestic); Wet or Dry ice (international) |
| RRID | AB_2533727 |
Target Information
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is DNA-dependent and is involved in regulating key cellular processes such as differentiation, proliferation, tumor transformation, and DNA damage recovery. Mutations in this gene may be associated with Fanconi anemia and type I diabetes pathophysiology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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