Thermo Fisher Scientific B4GALT6 Polyclonal Antibody
Human B4GALT6 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:20~1:50 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 연구용으로 적합하며, 장기 보관 시 -20°C에서 안정적 유지.
- 카탈로그번호
- PA563547
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human B4GALT6. Recombinant protein control fragment (Product # RP-103322) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638443 |
Product Specific Information
Immunogen sequence:
TTYLPENFTY SPYLPCPEKL PYMRGFLNVN VSEVSFDEIH QLFSKDLDIE PGGHWRPKDC KPRWK
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 88%
Target Information
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that have exclusive specificity for the donor substrate UDP-galactose and transfer galactose in a beta1,4 linkage to acceptor sugars such as GlcNAc, Glc, and Xyl.
Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures.
As type II membrane proteins, they include an N-terminal hydrophobic signal sequence directing the protein to the Golgi apparatus, which remains uncleaved as a transmembrane anchor.
By sequence similarity, beta4GalTs form four groups:
- beta4GalT1 and beta4GalT2
- beta4GalT3 and beta4GalT4
- beta4GalT5 and beta4GalT6
- beta4GalT7
The enzyme encoded by this gene is a lactosylceramide synthase important for glycolipid biosynthesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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