Thermo Fisher Scientific GTPBP3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GTPBP3 protein. Validated for Western blot and IHC (paraffin). Suitable for detecting mitochondrial GTP-binding protein involved in tRNA modification. Supplied in liquid form, 1 mg/mL, antigen affinity purifie...
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 276–492 of Human GTPBP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548797 |
Product Specific Information
- Recommended positive controls: NT2D1, IMR32, U87-MG
- Predicted reactivity: Bovine (81%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
Target Information
This gene encodes a GTP-binding protein localized to mitochondria, potentially involved in mitochondrial tRNA modification. Polymorphisms in this locus may influence the severity of aminoglycoside-induced deafness associated with 12S rRNA mutations. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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