Thermo Fisher Scientific PP2A alpha Polyclonal Antibody
PP2A alpha 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능. 고순도(>95%) 항원 친화 크로마토그래피로 정제. Human, Mouse, Rat 반응성. 연구용 전용 제품.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 261–309 of Human PP2A-alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803080 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
In eukaryotes, phosphorylation and dephosphorylation of proteins on serine and threonine residues regulate diverse cellular functions such as division, homeostasis, and apoptosis. Protein phosphatases are key enzymes in this process. The PP holoenzyme typically forms a trimeric complex consisting of regulatory, variable, and catalytic subunits. Four major families of protein phosphatase catalytic subunits are identified: PP1, PP2A, PP2B (calcineurin), and PP2C. The PP2A family includes PP2A alpha and PP2A beta subunits. Additionally, PPX (also known as PP4) is a putative member of a novel PP family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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