Thermo Fisher Scientific IGSF8 Polyclonal Antibody
Human IGSF8 단백질을 인식하는 Rabbit Polyclonal 항체로, WB와 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액에 보관됩니다. 세포 이동, 바이러스 감염 및 암 억제 연구에 활용 가능합니다.
- 카탈로그번호
- PA552875
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human IGSF8. Recombinant protein control fragment (Product # RP-89909) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642678 |
Product Specific Information
Immunogen sequence:
PDVLQVSAAP PGPRGRQAPT SPPRMTVHEG QELALGCLAR TSTQKHTHLA VSFGRSVPEA PVGRSTLQEV VGIRSDLAVE AGAPYAERLA AGELRLGKEG TDRYRMVVGG AQAGDAGTYH CTAAEWIQDP DGSWAQIAEK RAVLAHVDVQ
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 87%
- Rat: 87%
Target Information
This gene encodes a member of the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile) motif, and a variable number of immunoglobulin domains.
This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in cellular functions such as cell migration and viral infection.
It may also function as a tumor suppressor by inhibiting proliferation of certain cancers.
Alternate splicing results in multiple transcript variants that encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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