Thermo Fisher Scientific COL21A1 Polyclonal Antibody
인간 COL21A1 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot에 적합하며 1 µg/mL 권장. 합성 펩타이드 면역원으로 제작, 고순도 친화 크로마토그래피 정제. PBS+2% sucrose 용액에 0.09% sodium azide 포함, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human COL21A1 (aa 682–731) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2605969 |
Product Specific Information
Peptide sequence:
PGEPGYMGLP GIQGKKGDKG NQGEKGIQGQ KGENGRQGIP GQQGIQGHHG
Sequence homology:
- Dog: 93%
- Horse: 100%
- Human: 100%
- Pig: 100%
Target Information
COL17A1 is the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein and a structural component of hemidesmosomes, which mediate adhesion of keratinocytes to the underlying basement membrane. COL17A1 belongs to the FACIT collagen family (fibril-associated collagens with interrupted helices) and is localized to tissues containing type I collagen, helping maintain extracellular matrix integrity.
Diseases associated with COL17A1 dysfunction include epithelial recurrent erosion dystrophy and epidermolysis bullosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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