Thermo Fisher Scientific proGDNF Polyclonal Antibody
Rabbit polyclonal antibody targeting human proGDNF peptide (aa 54–66). Suitable for Western blot (1:200–1:1,000). Lyophilized form, 0.8 mg/mL concentration. Shipped at room temperature; store at -20°C. For research use only.
- 카탈로그번호
- PA577541
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Tested dilution 1:200–1:1,000
- Publications: Refer to Thermo Fisher Scientific references
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)PEDYPDQFDDVMD, corresponding to amino acid residues 54–66 of human GDNF (precursor) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736460 |
Product Specific Information
- Product is shipped at room temperature as a lyophilized powder.
- Store at -20°C upon receipt.
- Reconstitution: Add 50 µL of deionized water.
Target Information
GDNF (Glial cell line-derived neurotrophic factor) is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and shown to rescue these neurons in animal models of Parkinson’s disease.
GDNF is approximately 100 times more efficient as a survival factor for spinal motor neurons than neurotrophins. It enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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