Thermo Fisher Scientific C17orf37 Monoclonal Antibody (OTI1D7), TrueMAB
C17orf37 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합. 인간 시료 반응성, 무보존제 PBS 버퍼에 동결건조 형태로 제공. 재구성 및 결합 실험에 용이하며, 유방암 관련 바이오마커 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D7 |
| Immunogen | Full length human recombinant protein of human C17orf37 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The ERBB2 (neu/HER2) oncogene is a key predictor of patient outcomes and therapy responses in breast cancer.
C35 (C17orf37) is a novel tumor biomarker highly expressed in breast cancer. It is located on chromosome 17q12, 505 nucleotides from the 3′ end of the ERBB2 oncogene, which is the target for trastuzumab (Herceptin) therapy. The genes encoding C35 and ERBB2 are arranged tail-to-tail. The ORF37 open reading frame encodes a 12-kDa protein of unknown function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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