Thermo Fisher Scientific ADAT3 Polyclonal Antibody
인간 ADAT3 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P) 및 ICC/IF 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관. 연구용으로만 사용 가능.
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- PA563626
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Thermo Fisher Scientific ADAT3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ADAT3. Recombinant protein control fragment (Product #RP-99241). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637685 |
Product Specific Information
Immunogen sequence:
GAVRKLDADE DGLPYLCTGY DLYVTREPCA MCAMALVHAR ILRVFYGAPS PDGALGTRFR IHARPDLNHR FQVFRGVLEE QCRWLD
Highest antigen sequence identity to orthologs:
- Mouse: 86%
- Rat: 26%
Target Information
This gene encodes a subunit of a tRNA-specific adenosine deaminase. This heterodimeric enzyme converts adenosine to inosine in the tRNA anticodon.
A mutation in this gene causes a syndrome characterized by intellectual disability and strabismus.
This gene shares its 5′ exon with the overlapping gene, secretory carrier membrane protein 4.
ADAT3 (Adenosine Deaminase TRNA Specific 3) is a protein-coding gene.
Diseases associated with ADAT3 include:
- Neurodevelopmental Disorder With Brain Abnormalities, Poor Growth, And Dysmorphic Facies
- Cone-Rod Dystrophy 10
Related pathways:
- tRNA processing
- Processing of Capped Intron-Containing Pre-mRNA
Gene Ontology (GO) annotations related to this gene include hydrolase activity.
An important paralog of this gene is ADAT2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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