Thermo Fisher Scientific HHLA2 Polyclonal Antibody
Human HHLA2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Protein A로 정제된 액상 형태이며, 고농도(1 mg/mL)로 안정적. 면역 관련 연구 및 암 조직 분석에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human HHLA2 (amino acids 231–330) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01 M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
B7-H7 (also known as HHLA2) is a membrane protein with three Ig-like domains (IgV–IgC–IgV), unlike other B7 family members that typically have two domains (IgV–IgC).
B7-H7 shows 10–18% amino acid identity and 23–33% similarity to other B7 family proteins. It is broadly expressed in epithelial cells of the gallbladder, breast, kidney, colon, small intestine, and placenta.
In the immune system, HHLA2 is not constitutively expressed on human monocytes/macrophages but is widely expressed in various cancers, particularly in triple-negative breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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