Thermo Fisher Scientific RBFOX1 Polyclonal Antibody
RBFOX1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC(P), ICC/IF에 사용 가능하며, 인간 및 설치류 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태로, PBS/glycerol buffer에 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RBFOX1. Recombinant protein control fragment (Product #RP-98674). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646360 |
Product Specific Information
Immunogen sequence:
PAEYTAPHPH PAPEYTGQTT VPEHTLNLYP PAQTHSEQSP ADTSAQTVSG TATQTDDAAP TDGQPQTQPS E
Highest antigen sequence identity to orthologs:
- Mouse: 96%
- Rat: 96%
Target Information
Ataxin-2 binding protein 1 has an RNP motif highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene, which causes familial neurodegenerative diseases. Both ataxin-2 binding protein 1 and ataxin-2 are localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been identified, though not all full-length forms are determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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