Thermo Fisher Scientific Mouse CIDEA Synthetic Peptide

Thermo Fisher Scientific Mouse CIDEA Synthetic Peptide

Applications

• Control (Ctrl): Assay-dependent
• Blocking Assay (BLOCK): Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 15 amino acids near the carboxy terminus of mouse CIDE-A.
PEP-0034 can be used as a blocking peptide with polyclonal antibody PA5-19908.

Target Information

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue, and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.