Thermo Fisher Scientific SOCS7 Polyclonal Antibody
SOCS7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며 인간 SOCS7 N-말단 펩타이드(aa 35–84)를 면역원으로 제작. 액상 형태, 0.5 mg/mL 농도, PBS + sucrose buffer에 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human SOCS7 (aa 35–84) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610473 |
Product Specific Information
- Peptide sequence: LDPKALPPGL ALERTWGPAA GLEAQLAALG LGQPAGPGVK TVGGGCCPCP
- Sequence homology:
- Cow: 100%
- Human: 100%
- Mouse: 100%
- Pig: 100%
- Rabbit: 100%
- Rat: 100%
Target Information
SOCS7 regulates signaling cascades through protein ubiquitination and/or sequestration. It is involved in insulin signaling and glucose homeostasis by promoting IRS1 ubiquitination and proteasomal degradation. SOCS7 also inhibits prolactin, growth hormone, and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm, and reducing their DNA binding. It may act as a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex mediating ubiquitination and degradation of target proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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