Thermo Fisher Scientific AP3S2 Polyclonal Antibody
인간 AP3S2 단백질에 특이적인 토끼 폴리클로날 항체로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로 단백질 수송 및 리소좀 관련 경로 연구에 적합.
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Thermo Fisher Scientific AP3S2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human AP3S2. Recombinant protein control fragment (Product #RP-99268). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638049 |
Product Specific Information
Immunogen sequence:
LDLIFHMDKV HYILQEVVMG GMVLETNMNE IVAQIEAQNR LEKSEGGL
Highest antigen sequence identity to orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
AP3S2 (Adaptor Related Protein Complex 3 Subunit Sigma 2) is a protein-coding gene.
Related pathways include Lysosome.
Gene Ontology (GO) annotations: protein transporter activity.
An important paralog: AP3S1.
AP3S2 is part of the AP-3 complex, an adaptor-related complex not associated with clathrin.
The complex is localized to the Golgi region and peripheral structures, facilitating vesicle budding from the Golgi membrane and trafficking to lysosomes.
In conjunction with the BLOC-1 complex, AP-3 targets cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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