
Thermo Fisher Scientific TRIB2 Monoclonal Antibody (OTI8D11), TrueMAB
TRIB2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC, Flow cytometry에 적합. Human 시료 반응성. Affinity chromatography로 정제된 액상 항체이며, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8D11 |
| Immunogen | Full length human recombinant protein of human TRIB2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, homologous to protein serine-threonine kinases but lacking the active site lysine, likely resulting in loss of catalytic function. Tribbles proteins modulate signal transduction pathways in various physiological and pathological processes. This member induces apoptosis mainly in hematopoietic cells, is up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and acts as an oncogene that inactivates the transcription factor C/EBPalpha, contributing to acute myelogenous leukemia. Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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