Thermo Fisher Scientific PNN Polyclonal Antibody
Western blot, IHC, ICC/IF 등 다양한 응용에 적합한 Rabbit Polyclonal 항체. Human PNN 단백질의 209-239 아미노산 영역을 면역원으로 제작. Protein A 및 항원 친화 크로마토그래피로 정제. PBS 버퍼에 보관하며 장기 보관 시 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 | - |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 209–239 amino acids from the central region of human PNN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2552363 |
Product Specific Information
This antibody is predicted to react with bovine and mouse based on sequence homology.
Target Information
Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5′CAGGTG-3′. Capable of reversing CTBP1-mediated transcription repression.
Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
Participates in regulation of alternative pre-mRNA splicing and associates with spliced mRNA within 60 nt upstream of the 5′-splice sites.
Component of the PSAP complex, which binds RNA in a sequence-independent manner and regulates specific excision of introns in certain transcription subsets.
Involved in epithelial cell-cell adhesion and may act as a potential tumor suppressor for renal cell carcinoma.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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